SYSUCC Sun Yat-sen University Cancer Center

OUR DATABASES


qPTM
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Here, we updated our previous phosphorylation dynamics database qPhos to the qPTM. In qPTM, 11 482 553 quantification events among six types of PTMs, including phosphorylation, acetylation, glycosylation, methylation, SUMOylation and ubiquitylation in four different organisms were collected and integrated, and the matched proteome datasets were included if available.
An updated database for PTM dynamics in human, mouse, rat and yeast
Nucleic Acids Research
2023 Jan 6; 51(D1): D479–D487
doi: 10.1093/nar/gkac820

dbEBV
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dbEBV, a comprehensive database of EBV genomic variation landscape, which contains 942 EBV genomes with 109,893 variants from different tissues or cell lines in 24 countries. The database enables the visualization of information with varying global frequencies and their relationship with the human health of each variant. It also supports phylogenetic analysis at the genome or gene level in subgroups of different characteristics.
A database of Epstein-Barr virus variants and their correlations with human health
Computational and Structural Biotechnology Journal
Journal 23, 2024, 2076-2082
doi: 10.1016/j.csbj.2024.04.043

iHypoxia
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iHypoxia is an integrated resource for the expression dynamics of proteins in response to hypoxia (iHypoxia), and this database contains 2589 expression events of 1944 proteins identified by low-throughput experiments (LTEs) and 422,553 quantitative expression events of 33,559 proteins identified by high-throughput experiments from five mammals that exhibit a response to hypoxia.
An Integrative Database of Protein Expression Dynamics in Response to Hypoxia in Animals
Genomics, Proteomics & Bioinformatics
21, 2, Apr 2023, 267-277
doi: 10.1016/j.gpb.2022.12.001

ADDAGMA
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ADDAGMA database which hosts all publicly available microbe-phenotype associations data from domestic animal species. There are 4 animal species, including pig, cattle, horse and chicken from 356 publications curated into the database. The current version of ADDAGMA includes 290,422 quantification events (microbial abundance change) of 3,215 taxa associated with 48 phenotypes.
A database for domestic animal gut microbiome atlas
Computational and Structural Biotechnology Journal
20, Feb 2022, 897-898
doi: 10.1016/j.csbj.2022.02.003

qPTMplants
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qPTMplants, which hosts 1 242 365 experimentally identified PTM events for 429 821 nonredundant sites on 123 551 proteins under 583 conditions for 23 PTM types in 43 plant species from 293 published studies, with 620 509 quantification events for 136 700 PTM sites on 55 361 proteins under 354 conditions.
An integrative database of quantitative post-translational modifications in plants
Nucleic Acids Research
50, D1, 7, Jan 2022, D1497-D1499
doi: 10.1093/nar/gkab945

iCAV
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iCAV is a database that integrates the genomes of cancer-related viruses and the corresponding phenotypes. We collected a total of 18 649 genome sequences from seven human disease-related viruses, and each virus was further classified by the associated disease, sample and country. iCAV is a comprehensive resource of cancer-associated viruses that provides browse and download functions for viral genomes.
An integrative database of cancer-associated viruses
Database-The Journal of Biological Databases and Curation
2021, 2021, baab079
doi: 10.1093/database/baab079

iCysMod
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The iCysMod is a protein cysteine modifications database that curated and hosted the published 8 types of cysteine modification events including 85,747 sites on 31,483 proteins in 48 eukaryotes.
An integrative database for protein cysteine modifications in eukaryotes
Briefings in Bioinformatics
2021 Jan 7, bbaa400
doi: 10.1093/bib/bbaa400

gutMEGA
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The gutMEGA is a human gut metagenome database, which collated 182 literatures for human gut microbiome research. In total, 59,132 quantification events for 6,457 taxonomies at 7 different levels (kingdom, phylum, class, order, family, genus, and species) under 776 conditions were collected and integrated in the database, and the details about the samples and experiments were also curated.
A database of the human gut metagenome atlas
Briefings in Bioinformatics
2020 Jun 4, bbaa082
doi: 10.1093/bib/bbaa082

qPhos
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The qPhos database provides the curated quantitative phospho-proteome datasets in human tiss-ues and cell lines from published literatures to present the phospho-rylation dynamics under different conditions. In total, 3,537,533 quantification events for 199,071 sites on 18,402 proteins under 484 conditions are collected and inte-grated in the database.
A database of protein phosphorylation dynamics in humans
Nucleic Acids Research
2019 Jan 8;47(D1):D451-D458
doi: 10.1093/nar/gky1052